Amnesic syndrome after theophylline associated seizures: iatrogenic brain injury.
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Amnesic syndrome after theophylline associated seizures: iatrogenic brain injury.
Two patients developed a disabling amnesic syndrome after seizures associated with oral theophylline treatment. Such seizures are more likely in the elderly, in the presence of pre-existing neurological disease, and when theophylline is given with certain antibiotics and cimetidine. The mechanism of neuronal injury may be by the excessive release of endogenous excitotoxic glutamate.
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1994
ISSN: 0022-3050
DOI: 10.1136/jnnp.57.5.643